Journal of Advanced Pharmaceutical Science And Technology

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Advanced Pharmaceutical Science And Technology-PATENT APPLICATIONS

-Satheesh Podaralla

Research Scientist (Formulation R &D),
Biosciences Division,
SRI International, CA, USA.

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Satheesh Podaralla


Formulation R&D,
SRI International,
Menlo Park, CA.

Research Interests:


  • Perumal, OP, Satheesh K. Podaralla, Kaushik, RS. Method of forming non-immunogenic hydrophobic protein nanoparticles and uses therefor. United States Patent Application No. PCT/US2009/002935.
  • Perumal, O.P, Satheesh K. Podaralla, Averineni RK. Compositions and use of polymer conjugated protein micelles. United States Patent Application PCT/US2012/026484.
  • Perumal, O.P, Averineni RK Satheesh K. Podaralla. Protein based Nanocarriers for Topical Delivery of Retinoids. United States Patent Application PCT/US2012/026520.


  • American Association of Pharmaceutical Scientists (AAPS)
  • Controlled Release Society (CRS)
  • American Association of Cancer Research (AACR)




  • Satheesh Podaralla, Tulsi Ram Saini, Sistla Ramakrishna, Prakash V.Diwan-“Influence of microencapsulation method and peptide loading on insulin loaded poly (lactic-co-glycolic acid) microspheres in vitro and in vivo”. - Die Pharmazie 61 (2006), 613-617.
  • Satheesh Podaralla, Tulsi R. Saini, Chandrasekhar, Y.V.Kashyap, Sistla  Ramakrishna, Prakash  V.Diwan -   “Novel approach for delivery of insulin loaded poly (lactide-co-glycolide) nanoparticles using a combination of stabilizers”- Drug Delivery 14 (2007), 517-523.
  • Satheesh Podaralla, Perumal, O- Preparation of Zein nanoparticles by pH controlled nanoprecipitation. Journal of Biomedical Nanotechnology 6 (2010), 1-6.
  • Satheesh Podaralla, Perumal, O- Influence of formulation factors on the preparation of Zein nanoparticles. AAPS Pharm SciTech 13 (2012), 919-927.
  • Satheesh Podaralla, Averineni, R., Alqahtani, M., Perumal, O. Synthesis of novel biodegradable methoxy poly (ethylene glycol)-Zein micelles for effective delivery of curcumin. Molecular Pharmaceutics 9 (2012), 2778-2786.
  • P Sahdev, Satheesh Podaralla, R Kaushik, Perumal, O. Calcium phosphate nanoparticles for transcutaneous vaccine delivery. Journal of Biomedical Nanotechnology 9 (2013) 132-141.

Book Chapters

  • Satheesh K. Podaralla R., Kaushik, O., Perumal- Protein based nanoparticulate drug   delivery systems. Nanoparticulate Drug Delivery Systems II: Formulation and Characterization edited by Yashwant Pathak and Deepak Thassu, Informa Healthcare, New York, pp 69-91 (2009)
  • Perumal, O., Satheesh K. Podaralla- Preformulation. Pharmaceutical Manufacturing Handbook. Edited by Shayne Gad. John Wiley and Sons, Inc. pp 933-975 (2008).
  • Perumal, O., Satheesh K. Podaralla -Pharmaceutics and drug delivery research. In: From getting started in research to presenting data in a scientific paper. Edited by G. Jagadeesh, Y.K. Gupta and A. Prakash, Wolters-Kluwer, India pp 111-126 (2010).


  • Satheesh Podaralla, Elaine Struble, Jim Mckrew, Helen parish, Gita Shankar. “Development and evaluation of K777 HCl taste masked-oral formulations”. AAPS Annual meeting, October 14- 18th, 2012, Chicago, IL.
  • Satheesh Podaralla, Ranjith Averineni, Chandradhar Dwivedi, Omathanu Perumal. “Doxorubicin loaded Zein nanoparticles for treat drug resistant cancers”.  AAPS Annual meeting, October 14- 18th, 2012, Chicago, IL.
  • Satheesh Podaralla, Ranjith Averineni, Omathanu Perumal, Chandradhar Dwivedi, “Formulation development and evaluation of nanostructured lipid carriers for topical delivery of honokiol”. AACR Annual meeting, March 31- April 4th, 2012, Chicago, IL.
  • Satheesh K. Podaralla, Ranjith K. Averineni, and Omathanu P. Perumal, “Novel polyethylene glycol grafted Zein micelles for drug delivery applications” - The AAPS Annual Meeting and Exposition, October  2011, Washington, DC
  • Satheesh K. Podaralla, Hoffman, T, Kulkarni, P, Perumal, O: Optimization of preparation of Zein nanoparticles using Box-Behnken statistical design. AAPS- Annual meeting, New Orleans, LO, Nov 14-18, 2010
  • Satheesh K. Podaralla, and Omathanu P. Perumal, “Doxorubicin Loaded Zein Nanoparticles” - The 37th Annual Meeting and Exposition of the Controlled Release Society, July 2010, Portland, OR
  • Satheesh K. Podaralla, Radhey S. Kaushik, V.K. Venuganti, and Omathanu P. Perumal, “Role of particle size on phagocytic uptake and immunogenicity of protein based nanoparticles” –NBC, AAPS annual meeting, June 2009, Seattle, WA
  • Satheesh K. Podaralla, Radhey S. Kaushik, and Omathanu P. Perumal, “Preparation and Characterization of Novel Zein Nanoparticles for drug delivery Applications” -AAPS annual meeting, November 2008, Atlanta, GA