Journal of Antioxidant Activity

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Antioxidant Activity-A series of animal studies demonstrating that dietary supplement of polyphenol-rich products (bee propolis) prevents inflammatory diseases (inflammatory bowel disease-Kai Wang


Research Scientist

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Kai Wang


No.1 Beigou Xiangshan,
Haidian District,
China, 100093.

Research Interests:

  • A series of animal studies demonstrating that dietary supplement of polyphenol-rich products (bee propolis) prevents inflammatory diseases (inflammatory bowel disease, endotoxemia and acute pulmonary damage).
  • Studies in humans using faecal fermentation products and examining the effects of polyphenol-rich products (bee propolis) on gut microbiota changes.
  • Studies using cell models to clarify the molecular mechanisms of these anti-inflammatory effects. 


  • Dr Wang is currently a research scientist from Risk Assessment Laboratory for Bee Products Quality and Safety of Ministry of Agriculture of Institute of Apicultural Research, CAAS.
  • He obtained his PhD degree from College of Animal Sciences, Zhejiang University, China.
  • He used to be a visiting scholar in CSIRO Food and Nutrition in Adelaide, Australia.
  • He is recognized nationally and internationally for his scientific research in the areas of nutrition/natural products/healthy foods, particularly the mechanisms by polyphenol-rich foods and their constituents mitigate risk of serious inflammatory diseases, including endotoxemia and inflammatory bowel disease.
  • He is a reviewer of several SCI journals, including Cancer Letters, Journal of Functional Food, Mini-Reviews In Medicinal Chemistry, Mediators of Inflammation, etc.
  • He is also invited as a guest editor from the journal BioMed Research International.


  1. Kai Wang, Xiaolu Jin, Xiaoge Shen, Liping Sun, Liming Wu, Jiangqin Wei, Maria Cristina Marcucci Ribeiro, Fu Liang Hu and Jian-Xin Liu, Effects of Chinese propolis in protecting bovine mammary epithelial cells against mastitis pathogens induced cell damage, Mediators of Inflammation, 2016, In press.
  2. Kai Wang, Xiaolu Jin, Yifan Chen, Zehe Song,Xiasen Jiang,Fuliang Hu1, Michael A. Conlon, David L. Topping, Polyphenol-rich propolis extracts strengthen intestinal barrier function by activating AMPK and ERK signaling, Nutrients 2016, 8(5), 272
  3. Xiaolu Jin, Kai Wang (co-first author), Hongyun Liu, Fuliang Hu, Fengqi Zhao, and Jianxin Liu, Protection of Bovine Mammary Epithelial Cells from Hydrogen Peroxide-Induced Oxidative Cell Damage by Resveratrol, Oxidative Medicine and Cellular Longevity, 2016, Article ID 2572175
  4. Kai Wang, Lin Hu, Xiaolu Jin, Quanxin Ma, Maria Cristina Marcucci, Amandio Augusto Lagareiro Netto, Alexandra Christine Helena Frankland Sawaya, Shuai Huang, Wenkai Ren, Michael A. Conlon, David L. Topping and Fuliang Hu. Polyphenol-rich propolis extracts from China and Brazil exert anti-inflammatory effects by modulating ubiquitination of TRAF6 during the activation of NF-κB. Journal of Functional Foods, 2015, 19, 464-478
  5. Cui-Ping Zhang, Shun Ping, Kai Wang, Shuai Huang & Fu-Liang Hu. A survey of the incidence of poplar tree gum in propolis products on the Chinese retail market. Journal of Apicultural Research, 54(1): 30-35
  6. Jianglin Zhang, Xueping Cao, Shun Ping, Kai Wang, Jinhu Shi, Cuiping Zhang, Huoqing Zheng, Fuliang Hu. Comparisons of ethanol extracts of Chinese propolis (poplar type) and poplar gums based on theantioxidant activities and molecular mechanism. Evidence-Based Complementary and Alternative Medicine, Volume 2015, Article ID 307594, 15 pages
  7. Shuai Huang, Cui-Ping Zhang, Kai Wang, George Q. Li, Fu-Liang Hu. Recent advances in the chemical composition of propolis. Molecules, 2014, 19: 19610-19632;
  8. G.H. Dai,G.M. Meng, Y.L. Tong, X. Chen, Z.M. Ren, K. Wang, F. Yang. Growth-inhibiting and apoptosis-inducing activities of Myricanol from the bark of Myrica rubra in human lung adenocarcinoma A549 cells. Phytomedicine 21 (11), 1490-1496
  9. Kai Wang, Jianglin Zhang, Shun Ping, Quanxin Ma, Xuan Chen, Hongzhuan Xuan, Jinhu Shi, Cuiping Zhang, Fuliang Hu. Anti-inflammatory effects of ethanol extracts of Chinese propolis and buds from poplar (Populus × canadensis). Journal of Ethnopharmacology, 2014, 155: 300-311.
  10. Shuai Huang, Cui-Ping Zhang, George Q. Li, Yue-Yi Sun, Kai Wang and Fu-Liang Hu. Identification of catechol as a new marker for detecting propolis adulteration. Molecules, 2014, 19: 10208-10217.
  11. Hongzhuan Xuan, Zhen Li, Haiyue Yan, Qing Sang, Kai Wang, Qingtao He, Yuanjun Wang, and Fuliang Hu. Antitumor activity of Chinese propolis in human breast cancer MCF-7 and MDA-MB-231 cells. Evidence-Based Complementary and Alternative Medicine, Volume 2014, Article ID 280120, 11 pages. 
  12. Hongzhuan Xuan, Zhen Li, Jiying Wang, Kai Wang, Chongluo Fu, Jianlong Yuan, Fuliang Hu. Propolis reduces phosphatidylcholine-specific phospholipase C activity and increasing annexin a7 level in oxidized LDL-stimulated human umbilical vein endothelial cells. Evidence-Based Complementary and Alternative Medicine, Volume 2014, Article ID 465383, 9 pages