Chordomas

Chordomas are rare, slow-growing malignant tumors that form from cells of the incompletely developed notochord, a flexible cord of tissue that helps shape and support the spine and other parts of the body during early embryonic growth and development. Chordomas can occur at any age, but more commonly in adults, and can arise in any part of the spine or skull base. Chordomas are difficult to treat, and are often treated through surgery, radiation, and/or chemotherapy. Chordomas can be very serious and difficult to treat, requiring a multidisciplinary approach. The unique characteristics of chordomas, in terms of their biology, location, and treatment approaches, make them a challenge for scientists, physicians, and patients alike.