Journal of Biosemiotic Research

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Biosemiotic Research-Cellular Toxicity Evaluation (MTT assay) Animal Toxicity Studies including Acute (LD50) Sub-acute-Hamid Reza Rahimi's

Iran, Islamic Republic of

Kerman University of Medical Sciences (Kermān, Iran).

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Hamid Reza Rahimi's


Kerman University of Medical Sciences (Kermān, Iran).

Research Interests:

  • Cellular Toxicity Evaluation (MTT assay) Animal Toxicity Studies including Acute (LD50) Sub-acute 
  • Sub-chronic and Chronic Exposure to Drugs and Materials Organ Toxicity (specially liver toxicity)-Evaluation Protective Drugs or Plant Extracts Neuroscience
  • Behavior and Neurobiology Toxicology Mechanisms including Molecular
  • Cellular Biology
  • Receptor and Signaling Evaluations Nanotoxicology
  • Nanosafty and Ecotoxicology Clinical Toxicology and Patients Poisoning Hepato-Gastroenterology Pharmacology Immunotoxicology Microbiology and Antibiotics.



  • Jamalifar H, Rahimi HR, Samadi N, Shahverdi AR, Sharifian Z, Hosseini F, Eslahi H, Fazeli MR. Antimicrobial activity of different
  • Lactobacillus species against multi-drug resistant clinical isolates of Pseudomonas aeruginosa. Iran J Microbiol. 2011;3(1):21-25.
  • Ebadollahi Natanzi AR, Mahmoudian S, Rahimi HR, Mohammadpour M. Effects of some meteorological parameters and formulation on
  • phytotoxicity of the fungicide captan. Iran J Toxicol. 2011;5(14):488-494.
  • Rasouli M, Kalani M, Rahimi HR, Moravej A. Association of Interleukin-15 Single Nucleotide Polymorphisms with Resistance to
  • Brucellosis among Iranian Patients. Tissue Antigens. 2011;78(5):352-358.
  • Fouladdel S, Azizi E, Rahimi HR, Ostad SN. Determination of the Expression of COX-2 and Aromatase Protein in Parent and
  • Tamoxifen-resistant Subline of Human Breast Cancer T47D Cells. Inter J Pharmacol. 2011;7(6):710-715.
  • Hacopian N, Rahimi HR, Ghahremani MH, Hosseinzadeh Nik T, Ostad SN. Effects of continuous and interrupted forces on gene
  • transcription in periodontal ligament cells in vitro. Acta Medica Iranica. 2011;49(10):643-649.
  • Balouchzadeh A, Rahimi HR, Ebadollahi-Natanzi AR, Minaie B, Sabzevari O. Aqueous extract of Iranian green tea prevents lipid
  • peroxidation and chronic ethanol liver toxicity in rat. J Pharmacol Toxicol. 2011;6(8):691-700.
  • Nili-Ahmadabadi A, Rahimi HR, Tavakoli F, Hasanzadeh GR, Sabzevari O. Protective effect of pretreatment with thymoquinone against
  • Aflatoxin B1 induced liver toxicity in mice. DARU, Journal of Pharmaceutical Sciences. 2011;19(4):282-287.
  • Rahimi HR, Arastoo M, Shiri M. Punica granatum is more effective to prevent gastric disorders induced by helicobacter pylori or any
  • other stimulator in humans. Asian J Plant Sci. 2011;10(7):380-392.
  • Rahimi HR, Gholami M, Khorram-Khorshid HR, Gharibdoost F, Abdollahi M. On the protective effects of IMOD and silymarin
  • combination in a rat model of acute hepatic failure through anti oxidative stress mechanisms. Asian J Animal Vet Adv. 2012;7(1):38-45.
  • Rahimi HR, Arastoo M, Ostad SN. A comprehensive review of Punica granatum (Pomegranate) properties in toxicological,
  • pharmacological, cellular and molecular biology researches. Iran J Pharm Res. 2012;11(2):385-400.
  • Rahimi HR, Hasanli E, Jamalifar H. A mini review on new pharmacological and toxicological considerations of protease inhibitors'
  • application in cancer prevention and biological research. Asian J Cell Biol. 2012;7(1):1-12.
  • Rezvanfar MA, Rahimi HR, Abdollahi M. ADMET considerations for phosphodiesterase-5 inhibitors. Expert Opin Drug Metab Toxicol.
  • 2012;8(10):1231-1245.
  • Rahimi HR, Shiri M, Razmi A. Antidepressants can treat inflammatory bowel disease through regulation of the nuclear factor-κB/nitric
  • oxide pathway and inhibition of cytokine production: A hypothesis. World J Gastrointest Pharmacol Ther. 2012;3(6):83-5.
  • Abdolghaffari AH, Nikfar S, Rahimi HR, Abdollahi M. A. comprehensive review of antibiotics in clinical trials for inflammatory bowel
  • disease. Inter J Pharmacol. 2012;8(7):596-613.
  • Acute and subacute toxicity of novel biogenic selenium nanoparticles in mice. Shakibaie, M., Shahverdi AR, Faramarzi MA,
  • Hassanzadeh GR, Rahimi HR, Sabzevari O. Pharma Biol. 2013;51(1):58-63.
  • Rahimi HR, Rasouli M, Jamshidzadeh A, Farshad S, Firoozi MS, Taghavi AR, Kiany S. New immunological investigations on
  • Helicobacter pylori-induced gastric ulcer in patients. Microbiol Immunol. 2013;57(6):455-62.
  • Rahimi HR, Dehpour AR, Mehr SE, Sharifzadeh M, Ghahremani MH, Razmi A, Ostad SN. Lithium attenuates cannabinoid-induced
  • dependence in the animal model: involvement of phosphorylated ERK1/2 and GSK-3β signaling pathways. Acta Med Iran.
  • 2014;52(9):656-63.
  • Rahimi HR, Soltaninejad K, Shadnia S. Acute tramadol poisoning and its clinical and laboratory findings. J Res Med Sci. 2014
  • Sep;19(9):855-9.
  • Rahimi HR, Agin K, Shadnia S, Hassanian-Moghaddam H, Oghazian MB. Clinical and biochemical analysis of acute paint thinner.

Award & Honors:

  • 14th Iranian Pharmaceutical Sciences Congress (IPSC 2009), 1st Rank, Ahvaz, Iran 
  • Course Teaching 
  • Drug Information, Shiraz University (Jahad Daneshgahi of Fars), 2008-2010 
  • Toxicology and Pharmacology Laboratory Training of Pharmacy Student at Faculty of Pharmacy, TUMS, Tehran, Iran; 2010-2015 
  • Pharmacy Internship Training of Pharmacy Student of TUMS and Kish University of Medical Sciences (International Branch of TUMS); 2012-2015 
  • Pharmacology and Toxicology Courses For Pharmacy Students and Ms of Toxicology at KMU-2015-present.