Gene Therapy

Gene therapy is a promising medical technology that involves the insertion or replacement of genes or genetic material in order to treat a medical condition or disease. The aim of gene therapy is to replace or alter defective genes or to block the action of harmful genes or to introduce beneficial new genes. Gene therapy is used to treat a wide range of diseases, including cancer, inherited conditions and conditions caused by viruses, such as HIV/AIDS. It has shown promising results in treating conditions such as cystic fibrosis, Huntington's disease and muscular dystrophy. It is also being studied for its potential in treating Parkinson's disease, Alzheimer's disease, diabetes and cardiovascular diseases. Gene therapy holds the promise of a new era of personalized medicine, offering the treatment of diseases without relying on drugs and surgery.

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Related Articles

166 article(s) found

Evolutionary Conservation of Hox Genes in Vertebrate Brain Development

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Evaluation of Direct Cost of Adverse Drug Reactions to Highly Active Antiretroviral Therapy in Indian Human Immunodeficiency Virus Positive Patients

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Dual Choice for Dual Target Anti-HIV Therapy

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Single Nucleotide Polymorphisms associated with alimentary fatty liver disease are not genetic risk factors for treatment-associated hepatic steatosis in HIV patients on HAART

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When and How Should we be Measuring Adherence to Antiretroviral Therapy in Resource-Limited Settings?

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Pattern of Use of Highly Active Antiretroviral Therapy Regimens and Pattern of Occurrence of Adverse Drug Reactions in an Indian Human Immunodeficiency Virus Positive Patients

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Genetic Polymorphisms in Patients with Epilepsy: A Mini Review.

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Autoimmune Diseases: Genes, Inflammation And Environment

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Evaluating the Efficacy of Gene Silencing in Dopaminergic Neuronal Cells In-Vitro using Gold Nanorods (GNR) with Different Surface Properties Complexed to DARPP-32 siRNA.

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Molecular Cytogenetic Investigations in a Novel Chromosomal Abnormality of t(10;15)(q22;q22) in a Pediatric Precursor-B-Acute Lymphoblastic Leukemia Patient

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A Review of the Histologic, Genetic and Molecular Characteristics of Meningioma Pathogenesis and Progression

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Diagnostics of Progressive Multifocal Leukoencephalopathy in a Patient with Concomitant Lymphoma Infiltration of Central Nervous System During R-CHOP Chemotherapy- A Case Presentation and Review of the Literature.

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Exploration of the Implementation of Music Therapy into the Health Services: Lituanian Experience

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Mechanisms Associated with Acquisition of Resistance to Butyrate-Induced Apoptosis in Colorectal Cancer Cells Using Gene Expression Analysis

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Serrated Lesions of Colorectum: A New Pathway in Colorectal Carcinogenesis

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Haematological Disturbances in Dengue Haemorrhagic Fever - its Pathogenesis and Management Perspectives

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Epigenetics and Nutrition

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Anti-Oxidant Phytochemicals as Potential Treatments for Age-Related Macular Degeneration

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Tourette’s Syndrome: Medical, Educational and Behavior Therapy

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MicroRNA-1285 Might Potentially Regulate OCT4 Gene Expression by Direct Targeting of its Promoter

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Metabolic Correction Therapy as Adjuvant Treatment for Breast Cancer Patients: A Case Report

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Investigations of Molecular Evolutionary Mechanisms in Partially Sequenced Heat Shock Protein70 Homologue-Coding Gene of Olive Leaf Yellowing-Associated Virus Isolates from Tunisia

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The Role of BCL-2 and BAK Genes in Chronic Kidney Disease and Haemodialysis Patients

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Depression and Executive Dysfunction in Young Adults; Implications for Therapy

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Gene-Eden-VIR: A Potential Natural Treatment for Cervical Cancer

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Low Laser Therapy Plus Non-Surgical Periodontal Treatment Reduces Interleukin-1 Beta Serum Levels

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A study on the association of ACE i/D gene polymorphism, Obesity, Blood pressure and susceptibility of type 2 diabetes mellitus among the Kurmis of West Bengal, India.

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Evaluation of Household Radiation Exposure and Safety after Ambulatory Radioiodine Ablation Therapy

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Immune Thrombocytopenia after Allogeneic Stem Cell Transplantation: Case Report and Brief Overview of Treatment Strategies

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Fast Screening Method for Polymorphisms in Exon 9 of the Catalase Gene.

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Social Work in Psychosocial Crises: Analysis of a Voluntary Psychosocial Counseling Program to Close a Supply Gap in Psychosocial Therapy

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Emerging Paradigms in Regenerative Medicine: Stem cell Therapies

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Cognitive Behavior Therapy in The School Setting: A Case Study of A Nine Year Old Anxious Boy with Extreme Blushing

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Bioinformatic Analysis of Coronary Disease Associated SNPs and Genes to Identify Proteins Potentially Involved in the Pathogenesis of Atherosclerosis

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Dual Effects of Neuroprotection and Neurotoxicity by General Anesthetics on Neural Stem Cells: Role of Autophagy

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Dexamathasone Pulse Therapy in Refractory Childhood Seizure Disorders

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Combination of Radiation Therapy and Immunotherapy in the Treatment of Melanoma

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Rescuing Canavan Disease by Redirecting Metabolic Processing: Support for the Astrocyte Hypothesis of Canavan Disease Generation and A Possible Human Cure

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Effects of Music Therapy on The Mood of Family-Caregivers and Care Staffs and Relationships between Mood and Healing Sense in a Palliative Care Ward

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Protective Effect of Fennel Oil on Cyclophosphamide Inhibited Spermatogenesis and Induced Oxidative Stress in Albino Rats.

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Single Nucleotide Polymorphism Profiles of Patients with Acute Renal Rejection to Personalize Immunosuppressive Therapy: Preliminary Results from An On-Going, Italian Study

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Embryogenesis and Applications of Fingerprints- a review

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The Role and Effect of the Comprehensive Music Therapy in Project Sleep: A Multi-Disciplinary Quality Improvement Project.

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Pharmaceutical intervention on Ca2+/cAMP signaling interaction: benefits for combating neurodegeneration and diseases related to aging

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Early Versus Late Immunomodulatory Therapy in Vogt-Koyanagi-Harada disease

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Regulation of Expression of Reactive Oxygen Intermediates During Plasmodium Infection to Reduce Immunopathology Provides a Possible Antioxidant Adjuvant to Enhance Anti-Malarial Drug Therapy

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Combined Therapy Versus Usual Care in the Treatment of Depressed Cancer Patients with Pain

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Study of VCAM-1 Gene Expression in Normal and Tumoral Tissues in Patients with Colorectal Cancer

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Total Proteins, β- and γ-globulins as efficacy therapy response indicators in dogs infected with Leishmania infantum – a Review

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Identification and Expression Analysis of Fragaria Vesca MLO Genes Involved in Interaction with Powdery Mildew (Podosphaera Aphanis)

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International Journal of Chemotherapy and Practice; A Novel Journal for Therapeutic Researches

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Spatial Heterogeneity of Soil Respiration Response to Precipitation Pulse in a Temperate Mixed Forest in Central China

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Nanotechnology Meets Immunotherapy: CAR-T Cells Technology and Beyond

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Rice Epigenetic Pathways: Great Genetic Variation and Implication for Rapid Rice Breeding

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Study of Neuropilin-1/Cd304 Expression in Leukemogenesis

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General Evolution of the Universe Driven by Attraction and Four Levels of Biological Evolution as its Essential Part

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Successful Allogeneic Hematopoietic Stem Cell Transplantation from A 5/10 Mismatched Unrelated Donor in A Patient with Donor-Specific Anti-HLA Antibodies.

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Bisphenol A Down-Regulates The mRNA Expression of Steroidogenic Genes and Induces Histopathological Changes in Testes Of Rats

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Scientific and Technological Interventions for Attaining Precision in Plant Genetics and Breeding

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The Effect of Laser Irradiation on Reparative Osteogenesis

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Current Status and Future Perspectives of Gene Therapy for Heart Failure

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Endocrine Disrupting Chemicals: Epigenetic Relevance and Mechanisms

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Capsaicin: A Potential Therapy Adjuvant for Intestinal Bowel Disease

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Genetic Diversity of Large Japanese Field Mouse Apodemus speciosus Populations and Identification of their Food Plant Resources using DNA Barcoding in an Industrial Green Space

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Ozone Therapy in the Treatment of Periodontal Disease

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SCL-90-R and Suicide Ideation in Torture and War Survivors Receiving Psychotherapy

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Oncolytic Viruses: Can be Applicable Tools for Cancer Therapy?

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Dissociative Amnesia – A Challenge to Therapy  

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The Development and Evaluation of A Multiplex Real-Time PCR Assay for the Detection of ESBL Genes in Urinary Tract Infections

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Looking for the Best Journey: Real Methodology of Research in General Medicine

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Is the Measles Virus Indeed Involved in Carcinogenesis? – Commentary

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Method to Generate Electric Power and Hydrogen in the Absence Of External Energy

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Perioperative Period is a Critical Gap for Minimal Residual Cancer Cells Progression and Therapy: Biological and Molecular Based Evidences

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Genetic Diversity, Phylogenetic Tree and Principal Component Analysis Based on Morpho-Metric Traits of Assam Chilli

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"The 11 +" Warm-Up Program in Female Soccer Players and the Morpho-Physiological Changes Generated after its Implementation

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Epigenetic Biomarkers in Head and Neck Cancer 

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Long Non-Coding RNAs Emerging as Potential Epigenetic Biomarkers for Tobacco and/or Alcohol-Induced Head and Neck Cancer

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Avant Garde Alleviation -Cancer Immunotherapy

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Consequences of Repression of Emotion: Physical Health, Mental Health and General Well Being

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Trigonella Foenum Graecum Extract Benefits on Hematological, Biochemical and Male Reproductive System as a Complementary Therapy with Glimepiride in Treating Streptozotocin Induced Diabetic Rats

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Ontogenes and the Problem of Speciation

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D Allele and DD Genotype of I /D Polymorphism in The ACE Gene in Patients with Hypertension, Stroke And Cancer Prostate In Libreville: A Concern Given The High Frequencies of these Signatures in Gabonese Population

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Enhanced Healing and Bone re-Modelling by Low-Level Laser Therapy for Rapid Pain Control in Pediatric Fractures

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Research Status and Application Prospect of Epigenetic Regulation of BDNF Gene Expression in Chronic Pain 

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L162v Polymorphism of Par-Α Gene, A603g Polymorphism of Tissue Factor Gene and Risk of Coronary Heart Disease in Russian Population

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Characterization of rpoB Gene Mutations Associated with Rifampicin Resistance in Multidrug Resistant Tuberculosis Patients Co-infected with HIV from Southern India.

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Genetic-Mathematical Modelling of Mutational Processes in a Population

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Ultraviolet B Phototherapy Intervention in Patients with Multiple Sclerosis: A Prospective, Randomized Pilot Trial

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Allele Based Inference on Evolution and Extinction; A Genetic Drift Approach

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Type-2 Diabetes and Gene Therapy: The Promise of CRISPR Gene Therapy in type-2 Diabetes Mellitus

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Non-Enzymatic Methylglyoxal Formation From glucose Metabolites and Generation of Superoxide Anion Radical During Methylglyoxal-Dependent Cross-Links Reaction

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Molecular and Metabolic Pathogenesis of Familial Combined Hyperlipidemia and Association with Metabolic Syndrome

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Genes in Tumor Formation

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Possibility to Influence Treatment of Open Tibial Fracture by Negative Pressure Wound Therapy

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Role of Tie2, CD14, Angiopoietin as Angiogenetic Markers in Hepatocellular Carcinoma Complicating Hepatitis C Virus Infection

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Amino Acids and their Derivatives in Pathogenesis and Treatment of Liver Diseases

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Natural Selection in a Population is a Problem of Nonlinear Genetics

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A New Dietary Therapy for Chronic Renal Failure: Intestinal Dialysis Technology

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The Genetic Multiplicity- Multiple Endocrine Neoplasia type I

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A Qualitative Assessment of an Innovative Suicide Prevention and Treatment Approach: Contextual-Conceptual Therapy

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Evaluations of phylogenetic proximity in a group of 67 dogs with osteosarcoma: a pilot study

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Association of BsmI and ApaI Polymorphisms of the Vitamin D Receptor Gene with Dyslipidemia in Patients with Coronary Artery Disease.

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Practical Methods to Improve Client Compliance in General Medicine

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Structural Equation Modeling to Detect Predictors of CD4 Cell Count Change due to Long Term Antiretroviral Therapy Administered to HIV-Positive Adults at Felege Hiwot Teaching and Specialized Hospital, Bahir Dar, Ethiopia

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RETRACTED: Assessment of the Risk of Hemochromatosis in Polytransfused Sickle Cell Patients at the Abidjan Transfusion Therapy Unit

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The Mechanism of Decline of Senescent Skeletal Muscle Satellite Cell Self-Renewal and Regenerative Proliferation: The Role of Heparan Sulfate-FGF-2--FGFR1-p38αMAPK Axis, Sprouty1, miR-1, miR-133 and miR-29a

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The Intersection of Cultural Characteristics and Genetics on the Prevalence of Delayed Sleep Phase Syndrome in Brazilian and Japanese Adults

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Care in Chronic Diseases and in "Frail" Patients in General Practice

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Patient Safety and Clinical Risk Management for General Practice

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General Doctor's Consultation Work Begins before Entering the Patient and does not End when Patient Comes Out

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Molecular Study of Hepcidin HAMP (-582A/G) Gene Polymorphisms and Measurement of Serum Hepcidin Level among Sudanese Patients with Anemia of Chronic Kidney Disease

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Laboratory Tests Used in the Diagnosis of Immune Thrombocytopenia and General Treatment Approaches

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Molecular Analysis of 6-pyruvoyltetrahydropterin Synthase Gene in Atypical Phenylketonuric Egyptian Patients

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Genetic Algorithm Coupled with Neural Networks to Guesstimate the Subsurface Features of the Earth

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Rate, Maternal and Fetal Outcome of Cesarean Delivery Performed by IESO at Shenen Gibe General Hospital, Jimma South West Ethiopia: A Descriptive Retrospective Data

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Genetic-Mathematical Modelling of the Populations Interaction

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SARS-CoV-2 affected cells Pathogeny and Therapy

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Comparative Survival Assessment of Two-Dimension (2D) vs Three-Dimension (3D) Brachytherapy Treatment in Cervical Cancer: A Retrospective Case Control Study

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Effect of Hydroxychloroquine on Clinical Improvement and Mortality Among Patients with COVID-19 Admitted to Four General Hospitals in Saudi Arabia

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Cell Therapy as an Alternative approach for COVID-19 Infection Consequences: A Non-Systematic Review

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Exponential Parsimony to Generate Herd Immunity Against SARS- CoV2 Cybernetically Restricting Doxastic and Desiderative Logics

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Molecular Evolutionary Characteristics of the 2019 Novel Coronavirus (SARS-CoV-2) Contracted by Tunisian Citizens : Comparison and Relationship to Other Human and Animal Coronaviruses Based on Spike Glycoprotein-Coding Gene Sequences Analysis

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Some Regulation Mechanisms of Candidate Genes for Human Cardiovascular Diseases

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Generation of a Single-Domain Antibody against Isolated Escherichia Coli that Causes Camel-Calf Death

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A New Gene Mutation of PRKAR1A was found in a Carney Complex Case

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Antioxidative Protective Effect of Ozone Therapy on Isolated Mitochondria from Human Sperm

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From High-Risk Behaviors to Problem-Solving Strategies: Acceptance and Commitment Therapy Effects on Addiction Susceptible Adolescents in Cyberspace

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Exponential Parsimony to Generate Herd Immunity Against SARS- CoV2 Cybernetically Restricting Doxastic and Desiderative Logics

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Stem Cell Differentiation Stage Factors (SCDSFs) Taken from Zebrafish Embryo during Organogenesis and their Role as Epigenetics Regulators able to Reverse Neurosensory Hearing Loss

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Tay-Sachs Disease: From Molecular Characterization to Ethical Quandaries and the Possibility of Genetic Medicine

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Marginal SARS-CoV-2 Spike Protein Increases Interferon and Balances Cytokine Gene Expression

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Risk Management: Emerging critical issues during the hospital administration of drug therapy

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Willingness to take COVID-19 Vaccination among People Living with HIV/AIDS on Anti-Retroviral Therapy and Associated Factors in Woldia Comprehensive Specialized Hospital, Woldia, Ethiopia

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Detection of Smuggled Genetically Modified Crops and Assessment of its Environmental Impact in the Ethio -Sudan Trans Boundary Area, North West Ethiopia

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A General Approach to Modeling Covid-19

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Chemotherapy after whole-brain radiotherapy: a prognostic factor for metastatic breast cancer

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Interventional Programs for Genetically Disabled People Through Evidence-Based Advocacy

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Human Immunodeficiency Virus Drug Resistance (HIVDR) and Baseline Characteristics among Antiretroviral Therapy (ART) experienced Children and Adolescents under the care of Chidamoyo Christian Hospital in Hurungwe, Zimbabwe

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Is Vagus Nerve Therapy a Potential Alzheimer's Disease Treatment?

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Barriers to Managing Childhood Obesity in the General Practice Amidst of the Double Burden of Malnutrition: A Sri Lankan Perspective

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A Trio Study Showing Novel Gene Mutation In LAMB3 Causing Junctional Epidermolysis Bullosa (Intermediate/ Severe)

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RETRACTED: Leap into Fetal Surgery; In Utero Placental Mesenchymal Stem Cell Therapy, A Contemporary Approach to Treating Myelomeningocele

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Novel Methods for Inhibiting Amyloidogenesis in the Presence of Peptides to Block Hydrophobic Interactions

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Ontogenes in Drosophila Melanogaster and a Model of Speciation

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Rbm45 Phylogenetics, Protein Domain Conservation, and Gene Architecture in Clade Metazoa

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RETRACTED: A Microglia Initiated Target Therapy in Neuroinflammation for Alzheimer’s Patients

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A Network Pharmacology-Based Strategy For Predicting Therapy Targets Of Beta-Sitosterol In Treating Diabetic Retinopathy

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Understanding Inherited Bleeding Disorders: Genetic Mutations in Blood Coagulation Factors and Regulatory Proteins

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Ethics of Modern Stem Cell Research and Therapy: Current Critical and Interdisciplinary Perspectives

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Plasma TREM2 Levels, Alcohol Consumption, and Liver Enzymes in Patients with Alcohol use Disorder: A Sex-Dependent Relationship Involving MS4A6A Genetic Polymorphism

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Creative Process in Psychotherapy: Form and Structure as A Basis of Treatment

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Immunotherapy Usage Has Not Increased Sub-Lobar Pulmonary Resections Despite Reduced Pneumonectomies

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The Brainstem Auditory Evoked Potential: A Reinterpretation of its Electrogenesis

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Efficacy and Safety of Pulsed Magnetic Therapy in Sleep related Disorders: A Remote, Randomized, Double-Blind, Placebo-Controlled Trial

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Persistent Neovascular Exudation in Patients with Exudative Age-Related Macular Degeneration who have Choroid Imaging Biomarkers of Non-Neovascular Choroidal Pathology: Simultaneous Choroidal Hyperpermeability and Angiogenesis

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Caregiver-Child Co-Rumination and Treatment Outcomes in a Randomized Clinical Trial of Rumination-Focused Cognitive-Behavioral Therapy

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Retraction Note: Assessment of the Risk of Hemochromatosis in Polytransfused Sickle Cell Patients at the Abidjan Transfusion Therapy Unit

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Retraction Note: A Microglia Initiated Target Therapy in Neuroinflammation for Alzheimer’s Patients

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Retraction Note: Leap into Fetal Surgery; In Utero Placental Mesenchymal Stem Cell Therapy, A Contemporary Approach to Treating Myelomeningocele

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Existential Therapy and the Contextual Model: Unified by Presence, Flexibility, and Meaning-Making

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To Achieve High-Quality Agricultural Development is the General Trend of the Times

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Review: The Role of Human Papillomavirus in Virus-Induced Carcinogenesis

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HIV-Associated Peripheral Neuropathy and Antiretroviral Therapy: A Prospective Study from a Tertiary Care Centre in South India

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How Intensive Short-Term Dynamic Psychotherapy Merges with Hypnotism and Solution- Focused Methods

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Conjunctival Resection for Mooren's Ulcer Refractory to Medical Therapy: A Case Report

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The Effectiveness of Cognitive-Analytic Therapy in Women Diagnosed with Breast Cancer and Post-Traumatic Stress Disorder

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