Familial Adenomatous Polyposis (FAP)

Familial adenomatous polyposis (FAP) is an inherited disorder that causes polyps or growths in the lining of the colon. These polyps can increase the risk of developing colorectal cancer, and if untreated, the risk rises significantly. With FAP, polyps form in the lining of the intestine from an early age, increasing the risk of colorectal cancer and other related complications including polyp-related abdominal pain and obstruction. FAP is relatively rare, with an estimated incidence of 1 in 8,000-10,000 individuals. Treatment options for FAP include the removal of the entire colon and rectum, followed by reconstructive surgery. Regular surveillance and genetic testing are also important for individuals at risk for FAP.