Wistar Rats

Wistar rats are a common rodent model used in scientific research. These rats were first bred in the early 20th century by Dr. Henry Donaldson and his colleagues at the Wistar Institute in Philadelphia. The breeding process produced a strain of rats that had a consistently high level of reproductive success and were therefore easily maintained in research laboratories. Wistar rats are commonly used in a variety of scientific studies, including toxicology, pharmacology, and physiology. They are particularly well-suited for research in these areas due to their docile nature, ease of handling, and strong reproductive capacity. Their predictable behavior and physiological responses make them an excellent model for studying a wide variety of biological, chemical, and environmental factors. One major advantage of using Wistar rats is that their genetics and physiology closely resemble those of humans. This similarity allows scientists to use the rats as predictive models for testing the efficacy and safety of new drugs and other therapeutic compounds. Additionally, their genetic uniformity makes it easier to test treatments across multiple rats, which enhances the accuracy and reliability of study results. Overall, Wistar rats are a valuable tool in the scientific community due to their predictability, consistency, and genetic similarity to humans. Their use in research has helped to advance our understanding of many diseases and conditions and has led to the development of new and more effective treatments.

← Journal of Current Scientific Research

Related Articles

34 article(s) found

Early Glycine Supplementation Re-Establishes Adrenal Catecholamine Secretion in Hypothalamic Obesity Model in Rats but does not Affect Visceral Adiposity.

Full-text HTML Download PDF Download XML

Protective Effect of Fennel Oil on Cyclophosphamide Inhibited Spermatogenesis and Induced Oxidative Stress in Albino Rats.

Full-text HTML Download PDF Download XML

Comparative Study of Hypolipidemic Effects of Momordica Charantia (Karela) with Atorvastatin in Fat Fed Rats

Full-text HTML Download PDF Download XML

Bisphenol A Down-Regulates The mRNA Expression of Steroidogenic Genes and Induces Histopathological Changes in Testes Of Rats

Full-text HTML Download PDF Download XML

Lipopolysaccharide Prompts Oxidative Stress and Apoptosis in Rats’ Testicular Tissue

Full-text HTML Download PDF Download XML

Changes in Rats’ Liver Structure Induced by Zinc Oxide Nanoparticles and the Possible Protective Role of Vitamin E

Full-text HTML Download PDF Download XML

Beneficial Effects of Fennel (Foeniculum Vulgare) in Treating Obesity in Rats

Full-text HTML Download PDF Download XML

Interaction Between Ator and Fennel in the Treatment of Obesity in Rats

Full-text HTML Download PDF Download XML

Trigonella Foenum Graecum Extract Benefits on Hematological, Biochemical and Male Reproductive System as a Complementary Therapy with Glimepiride in Treating Streptozotocin Induced Diabetic Rats

Full-text HTML Download PDF Download XML

Exercise and Vitamin D Supplementation Modify Spleen Morphology in Lean, but not, in Monosodium-Glutamate-Obese Rats

Full-text HTML Download PDF Download XML

Changes in Adult Rats’ Testis structure Induced by Hypothyroidism and Alleviating Role of L-Carnitine

Full-text HTML Download PDF Download XML

Effect of a High Fat and High Protein Diet on Exercise-Induced Skeletal Muscle Hypertrophy in Rats

Full-text HTML Download PDF Download XML

The Effect of Aqueous Extract of Ocimum gratissium (Linn) on 1, 2 - Dimethyl Hydrazine induced Colon Cancer in Male Wistar Rats

Full-text HTML Download PDF Download XML

Auricularia Polytricha (Mushroom) Regulates Testicular DNA Expression and Oxidative Stress Markers of Streptozotocin-Induced Diabetic Male Wistar Rat

Full-text HTML Download PDF Download XML

Effects of Aluminium Sulphates on Weight and Structure of Adrenal Gland of Adult Wistar Rats

Full-text HTML Download PDF Download XML

Effects of Selected Secondary Metabolites in Leaf Extract of Jatropha Tanjorensis on Some Gonadal Hormones in Male Wistar Rats

Full-text HTML Download PDF Download XML

Prevention of Aging and Improvement of Longevity and Life-Span in D-Galactose Induced Aging Rats After Treatment with the Biofield Energy Per Se and Biofield Treated Proprietary Test Formulation

Full-text HTML Download PDF Download XML

Evaluation of Biological Activities of Opuntia Ficus Indica Cladodes Extract Against Cadmium-Induced Osteoporosis in Male Wistar Rats

Full-text HTML Download PDF Download XML

Effect of Trigonella Foenum against Ethylene Diamine Tetra Acetic Acid induced Nephrotoxicity in Male Albino Rats

Full-text HTML Download PDF Download XML

Biological Effects of High Radiofrequency Radiation on Wistar Rats: A Literature Review

Full-text HTML Download PDF Download XML

Effect of Wheat Germ, Wheat Germ Oil on Lipid Profile of Hypercholesterolemic Rats

Full-text HTML Download PDF Download XML

Evaluation of Anti-oxidation and Therapeutic Effect of Biofield Energy Healing Based Novel Test Formulation Using TNBS (Tri Nitro Benzene Sulfonic Acid) - Induced Ulcerative Colitis in Sprague Dawley Rats

Full-text HTML Download PDF Download XML

Evaluation of Vitamin D3 metabolite (25-OH Vit D3), Neurotransmitter (ACh), and the Expression of Proinflammatory Cytokines (IL-6 and TNF-α) in Tissue Homogenate after Administration of Biofield Energy Healing-based Novel Proprietary Test Formulation and Biofield Treatment per se to the Animals in Vitamin D3 Deficiency Diet (VDD)-induced Sprague Dawley Rats

Full-text HTML Download PDF Download XML

Antioxidant Activity of Biofield Treated Proprietary Test Formulation Supplemented with Vitamins and Minerals in Vitamin D3 Deficiency Diet (VDD) Induced Sprague Dawley Rats

Full-text HTML Download PDF Download XML

Evaluation of Renal and Cardioprotective Potential of the Biofield Energy Treated Proprietary Test Formulation on L-NAME and High Fat Diet-Induced Cardiovascular Disorders in Sprague Dawley Rats

Full-text HTML Download PDF Download XML

Evaluation of Immunomodulatory Effect of a Novel Test Formulation in D-Galactose-Induced Aging Dysfunction in Sprague Dawley Rats

Full-text HTML Download PDF Download XML

Evaluation of Antioxidative Potential of the Biofield Energy Treated Proprietary Test Formulation on L-NAME and High Fat Diet-Induced Cardiovascular Disorders in Sprague Dawley Rats

Full-text HTML Download PDF Download XML

Evaluation of Cardiac Performance after Treatment with the Biofield Energy Treated Proprietary Test Formulation on L-NAME and High Fat Diet-Induced Cardiovascular Disorders in Sprague Dawley Rats

Full-text HTML Download PDF Download XML

Antioxidant and Anti-Inflammatory Activities of Biofield Energy Treated Proprietary Test Formulation in Brain Tissues in Cecal Slurry, LPS and E. Coli-Induced Systemic Inflammatory Response Syndrome (SIRS) in Sprague Dawley Rats

Full-text HTML Download PDF Download XML

Evaluation of Inflammatory Serum Cytokines after Treatment with the Consciousness Energy Healing Based Proprietary Test Formulation on Combination of Cecal Slurry, LPS and E. Coli Induced Systemic Inflammatory Response Syndrome (SIRS) in Sprague Dawley Rats

Full-text HTML Download PDF Download XML

Evaluation of Antioxidative Potential of the Biofield Energy Treated Proprietary Test Formulation on L-NAME and High Fat Diet-Induced Cardiovascular Disorders in Sprague Dawley Rats

Full-text HTML Download PDF Download XML

Effect of Extracts of Dialium guineense Stem Bark on Lipid Profile and CCl4- Induced Histological Changes in Liver of Wistar Rats

Full-text HTML Download PDF Download XML

Histomorphomertric Analysis Of Hormonal Contraceptive Pills On Anterior Pituitary Gland In Female Wister Rats

Full-text HTML Download PDF Download XML

Pain Perception Modulates Synaptic and Somatic Plasticity in the Dentate Gyrus of Rats

Full-text HTML Download PDF Download XML