Research Topic · Peer-Reviewed

Nicotine

Nicotine is a pyridine alkaloid naturally present in tobacco and the principal psychoactive and addictive constituent of tobacco products. It acts as an agonist at nicotinic acetylcholine receptors in the central and peripheral nervous systems, stimulating dopaminergic reward pathways that drive dependence, while al…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 62× across the literature 🔖 ISSN 2473-1005 🗓 Reviewed July 2026

Overview

Nicotine is a pyridine alkaloid naturally present in tobacco and the principal psychoactive and addictive constituent of tobacco products. It acts as an agonist at nicotinic acetylcholine receptors in the central and peripheral nervous systems, stimulating dopaminergic reward pathways that drive dependence, while also exerting sympathomimetic cardiovascular effects through catecholamine release. Nicotine reaches the body by combustible smoking, smokeless tobacco, and increasingly through electronic cigarettes and vaping devices, each delivering nicotine alongside other constituents of differing toxicological profiles. In the oral cavity and upper aerodigestive tract, tobacco and nicotine exposure are associated with mucosal and periodontal effects, altered oral microbial populations, impaired wound healing relevant to implant and surgical outcomes, and elevated risk of oropharyngeal and other malignancies; emerging products such as e-cigarettes raise distinct public-health concerns. Because dependence is the core barrier to cessation, behavioral and pharmacological interventions, self-efficacy, and population-level tobacco-control policy are central to reducing harm. The journal publishes peer-reviewed research spanning the health effects of smoking and vaping, oral and cardiovascular consequences of tobacco use, cancer risk, smoking-cessation strategies, and tobacco-control measures, reflecting the clinical and public-health dimensions of nicotine and tobacco exposure.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2020

From Smoking to Vaping: What does Judaism have to Say?

Turner AkivaCorresponding author
Chair and Professor, Department of Health Science, Nova Southeastern University, USA
Exact topic Public Health International Cited by 2 doi:10.14302/issn.2641-4538.jphi-20-3163
2019

Surgical Site Infections: A Still Ongoing Challenge

A. S. Sardenberg RodrigoCorresponding author
Chief of Thoracic Surgery, Hospital Paulistano, Americas Serviços Médicos São Paulo, Brazil
Exact topic International Journal of Infection Prevention Cited by 2 doi:10.14302/issn.2690-4837.ijip-18-2515

How this research is being cited

The 12 articles above have been cited 62 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Nicotine, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Dentistry And Oral Implants (ISSN 2473-1005).

Journal editorial board
Austin Lin Yee · United States Janet H. Southerland · United States Brian Muzyka · United States

This page summarises published research for orientation; it is not medical or professional advice.