Collision-induced Dissociation

Overview

Collision-induced dissociation is a fragmentation technique used in mass spectrometry where ions are accelerated and collide with neutral gas molecules, causing them to break apart into smaller fragment ions that reveal structural information about the original molecule. Research published in Developments in Mass Spectrometry addresses the application of this technique within liquid chromatography-mass spectrometry systems for food safety analysis. The journal's coverage examines how collision-induced dissociation contributes to the identification and quantification of contaminants, adulterants, and other compounds of concern in food matrices, where fragmentation patterns generated through controlled collisions enable analysts to confirm molecular structures and distinguish between closely related substances. This topic matters because accurate identification of food components and contaminants requires not only measuring molecular mass but also obtaining detailed structural information that can differentiate between isomers and verify the presence of specific compounds. The controlled fragmentation achieved through collision-induced dissociation provides this essential confirmatory capability, supporting regulatory compliance and protecting public health by enabling laboratories to detect and characterize potentially harmful substances in the food supply with greater certainty than mass measurement alone would allow.

Research published in this journal

1 peer-reviewed article, ranked by relevance. Each links to its DOI.

This page summarises published research for orientation; it is not medical or professional advice.

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