Shotgun Sequencing

Shotgun sequencing is a method used for DNA sequencing. It refers to a process in which the genome is fragmented into smaller pieces, and those pieces are sequenced to eventually build a larger map of the entire genome. This method is useful for sequencing large genomes, such as the human genome, that would be too difficult and expensive to sequence in one piece. It is also useful for sequencing genomes of unknown size, such as microbes. Shotgun sequencing is highly accurate, and is now the most commonly used method of sequencing genomes. In addition to sequencing entire genomes, shotgun sequencing is commonly used in biomedical research to identify genes, discover new species, and study the evolution of organisms.