Stress Granule
A stress granule (SG) is a structure where mRNA molecules, their regulatory proteins and associated mRNPs temporarily aggregate in a cell in response to environmental stress. SG formation can repress or modify protein expression caused by the mRNA in the granule. SGs are part of the cellular stress response mechanism and play a role in the regulation of gene expression. SGs have been associated with diseases including cancer and Alzheimer's, as their formation and regulation can be used as a therapeutic target.
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