Epithelial-Mesenchymal Transition (EMT)

Epithelial-Mesenchymal Transition (EMT) is a process in which cells transition from an epithelial to a mesenchymal state. It has been identified as important for embryonic development, tissue and organ regeneration, and tumor metastasis. Through EMT, epithelial cells are able to lose their cell adhesive links, enabling them to migrate and form distinct cellular structures. Understanding the role of EMT in cancer progression is of critical importance for the development of novel strategies for the diagnosis and treatment of cancer.