Genetic Factors
in Coronary Artery Disease Coronary artery disease (CAD) is a condition where the arteries that supply the heart with blood become narrowed and hardened due to the buildup of fatty substances, calcium, and other substances. Genetic factors have been well established as a major influence in the development of CAD. An individual's genetic makeup can influence their risk of developing CAD through genetic abnormalities, family history of the disease, and lifestyle or environmental risk factors. Research has shown that certain mutations in genes involved in cholesterol and fat metabolism and inflammation can increase the risk of developing CAD. Additionally, certain gene variants have been linked to the efficacy of treatments for CAD. Understanding the genetic basis of CAD is important for identifying susceptible individuals and providing tailored treatments for the disease.
← Journal of Genetic Engineering