Nuclear magnetic resonance (NMR) spectroscopy is an analytical technique that exploits the magnetic properties of atomic nuclei, such as hydrogen-1, carbon-13, and phosphorus-31, to determine molecular structure, dynamics, and purity. In a strong magnetic field, nuclei with nonzero spin resonate at characteristic ra…
Nuclear magnetic resonance (NMR) spectroscopy is an analytical technique that exploits the magnetic properties of atomic nuclei, such as hydrogen-1, carbon-13, and phosphorus-31, to determine molecular structure, dynamics, and purity. In a strong magnetic field, nuclei with nonzero spin resonate at characteristic radiofrequencies; the resulting chemical shifts, coupling constants, and integration patterns report on the electronic environment and connectivity of atoms, allowing complete elucidation of organic and biochemical structures. Within Glycomics And Metabolism, NMR is indispensable for assigning the configuration and linkage of carbohydrates, confirming stereochemistry, and characterizing reaction products. The articles assembled here apply structural characterization to the synthesis of N-glycosyl amides from glycosyl oxazolines, the preparation of modified purine nucleoside analogues such as cladribine and clofarabine, and the vibrational and density-functional analysis of heterocyclic compounds, alongside complementary mass-spectrometric methods. NMR is routinely paired with chromatography and mass spectrometry to verify identity and detect adulterants in complex mixtures. Its non-destructive, quantitative nature makes it central to synthetic confirmation, metabolite profiling, and the study of carbohydrate-active reactions. Mastery of one- and two-dimensional NMR experiments underpins rigorous structure proof in carbohydrate chemistry, nucleoside drug design, and metabolic research.
10 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 10 articles above have been cited 27 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on NMR Spectroscopy, linking to each citing work.