Dyneins

Dyneins are microtubule motor proteins responsible for the movement of cilia, flagella, and intracellular organelles. They're vital components of the 'molecular motors' which drive the cell's internal movements. Dyneins are essential for a wide range of biological processes including powering the vital beating of cilia, motility of sperm, and the transport of molecules around the cell. The malfunction of dyneins has been linked to a number of diseases, including cystic fibrosis and primary ciliary dyskinesia. In recent years, great effort has been made to understand the complex structure of dyneins, and the development of therapies to help treat these diseases.