Overview
Lyophilization, commonly known as freeze-drying, is a dehydration technique that removes water from a material by freezing it and then subliming the ice directly into vapour under reduced pressure, bypassing the liquid phase. Because the process operates at low temperature, it preserves heat-sensitive substances far better than conventional drying, retaining structure, activity, and chemical integrity. The result is a dry, stable product that can be stored for long periods and reconstituted by adding water when needed. Lyophilization is widely applied in chemistry, biochemistry, and the pharmaceutical and food industries to preserve proteins, enzymes, vaccines, biological specimens, reagents, and delicate compounds. It also concentrates and purifies samples by removing solvent, making it a valuable step in analytical and preparative workflows. These applications, spanning the handling and stabilization of sensitive chemical and biological materials, fall within the scope of new developments in chemistry. This page gathers peer-reviewed, open-access research relevant to lyophilization and the preservation and processing of heat-sensitive materials.
Research published in this journal
2 peer-reviewed articles, ranked by relevance. Each links to its DOI.
How this research is being cited
The 2 articles above have been cited 21 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · ACS Applied Nano Materials
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2025 · Organic & Biomolecular Chemistry
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Abdullah H. Alluhayb et al. · 2025 · Results in Chemistry
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2025 · International Journal of Biological Macromolecules
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2025 · International Journal of Biological Macromolecules
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2025 · Results in Chemistry
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Maretha Nur Rohma et al. · 2025 · JURNAL PIJAR MIPA
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Liliana Anchidin-Norocel et al. · 2024 · International Journal of Electrochemical Science
A sample of recent works citing this journal's research on Lyophilization, linking to each citing work.