Journal of Public Health International

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Public Health International-Neuroinflammation in Central Nervous System (CNS) and Peripheral Nervous System (PNS)-Yan Wang

United States

Department of Pediatrics,
The University of North Carolina at Chapel Hill.

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Yan Wang


Postdoctoral Research Associate,              
Department of Pediatrics,
The University of North Carolina at Chapel Hill.

Research Interests:

  • Neuroinflammation in Central Nervous System (CNS) and Peripheral Nervous System (PNS)
  • Epigenetic modifications in T cells 
  • Pathogenic mechanisms in Autoimmune Diseases
  • Pathogenic mechanisms and signal transduction pathways in ageing-associated diseases
  • Stem cell dynamics, neurogenesis, neuronal regeneration, apoptosis and autophagy


  1. Wang Y, Nag M, Tuohy J, De Paris K, Fogle J (2017), T regulatory cell induced Foxp3 binds the IL2, IFNγ, and TNFα promoters in virus-specific CD8+ T cells from feline immunodeficiency virus infected cats. AIDS Research and Human Retroviruses.
  2. Wang Y, Nag M, Tuohy J, Fogle J (2017), Micro-RNA 10a is increased in feline T regulatory cells and increases Foxp3 protein expression following in vitro transfection. Vet. Sci. 2017, 4, 12.
  3. Raza, M.U., Tufan, T., Wang, Y. Hill, H., and Zhu MY., (2016), DNA Damage in Major Psychiatric Diseases. Neurotox Res (2016) 30: 251.
  4. Wang Y, Hilton BA, Cui K, Zhu MY (2015), Effects of antidepressants on DSP4/CPT-induced DNA damage response in neuroblastoma SH-SY5Y cells. Neurotox Res 28(2):154-70.
  5. Wang Y, Musich PR, Cui K, Zou Y, Zhu MY (2015), Neurotoxin-Induced DNA Damage is Persistent in SH-SY5Y Cells and LC Neurons. Neurotox Res 27(4):368-83.
  6. Wang Y, Musich PR, Serrano MA, Zou Y, Zhang J, Zhu MY (2014) Effects of DSP4 on the Noradrenergic Phenotypes and Its Potential Molecular Mechanisms in SH-SY5Y Cells. Neurotox Res 25:193-207.
  7. Wu JC, Qi L, Wang Y, Kegel KB, Yoder J, Difiglia M, Qin ZH, Lin F (2012), The regulation of N-terminal Huntingtin (Htt552) accumulation by Beclin1. Acta Pharmacol Sin 33:743-751.
  8. Zha Q, Wang Y, Fan Y, Zhu MY (2011) Dexamethasone-induced up-regulation of the human norepinephrine transporter involves the glucocorticoid receptor and increased binding of C/EBP-beta to the proximal promoter of norepinephrine transporter. J Neurochem 119:654-663.
  9. Wang Y, Lin F, Qin ZH (2010), The role of post-translational modifications of huntingtin in the pathogenesis of Huntington's disease. Neurosci Bull 26:153-162.