Journal of Spine and Neuroscience

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Spine and Neuroscience-Developmental Neuroscience-Jun Cai

United States

University of Louisville, USA

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Jun Cai

Address:

570 S. Preston St., Baxter I, Suite 321B

Research Interests:

Developmental Neuroscience, Cardiovascular complications of diabetes and obesity, Antioxidant metallothionein and its preventive effect on oxidative damage, Trace element (Zinc, copper, iron) homeostasis, Low-dose radiation.

Biography:

Publications:

  1. Liu Y, Shields LBE, Gao Z, Wang Y, Zhang YP, Chu T, Zhu Q, Shields CB, Cai J. Current Understanding of Platelet-Activating Factor Signaling in Central Nervous System Diseases. Mol Neurobiol. 2017 Sep;54(7):5563-5572
  2. Wang Z, Huang Y, Cheng Y, Tan Y, Wu F, Wu J, Shi H, Zhang H, Yu X, Gao H, Lin L, Cai J, Zhang J, Li X, Cai L, Xiao J.Endoplasmic reticulum stress-induced neuronal inflammatory response and apoptosis likely plays a key role in the development of diabetic encephalopathy. Oncotarget. 2016 Nov 29;7(48):78455-78472
  3. Gourévitch B, Cai J, Mellen N. Cellular and network-level adaptations to in utero methadone exposure along the ventral respiratory column in the neonate rat.    Exp Neurol. 2016 Mar 20. pii: S0014-4886(16)30063-2.
  4. Wang Y, Gao Z, Zhang Y, Feng SQ, Liu Y, Shields LBE, Zhao YZ, Zhu Q, Gozal D, Shields CB, Cai J. Attenuated Reactive Gliosis and Enhanced Functional Recovery Following Spinal Cord Injury in Null Mutant Mice of Platelet-Activating Factor Receptor. Mol Neurobiol. 2016 Jul;53(5):3448-3461
  5. Zhou S, Yin X, Jin J, Tan Y, Conklin DJ, Xin Y, Zhang Z, Sun W, Cui T, Cai J, Zheng Y, Cai L. Intermittent hypoxia-induced cardiomyopathy and its prevention by Nrf2 and metallothionein. Free Radic Biol Med. 2017 Aug 2;112:224-239.
  6.  Zhao YZ, Jiang X, Lin Q, Xu HL, Huang YD, Lu CT, Cai J. Thermosensitive heparin-poloxamer hydrogels enhance the effects of GDNF on neuronal circuit remodeling and neuroprotection after spinal cord injury.  J Biomed Mater Res A. 2017 Jun 7
  7.  Wang S, Gu J, Xu Z, Zhang Z, Bai T, Xu J, Cai J, Barnes G, Liu QJ, Freedman JH, Wang Y, Liu Q, Zheng Y, Cai L.  Zinc rescues obesity-induced cardiac hypertrophy via stimulating metallothionein to suppress oxidative stress-activated BCL10/CARD9/p38 MAPK pathway.  J Cell Mol Med. 2017 Jun;21(6):1182-1192. 
  8.  Liu Y, Shields LBE, Gao Z, Wang Y, Zhang YP, Chu T, Zhu Q, Shields CB, Cai J. Current Understanding of Platelet-Activating Factor Signaling in Central Nervous System Diseases. Mol Neurobiol. 2017 Sep;54(7):5563-5572.