Necrosis is a form of cell and tissue death that occurs when cells are damaged by injury, infection, loss of blood supply, or exposure to toxins, leading to their uncontrolled breakdown within living tissue. Unlike the orderly, programmed process of apoptosis, necrosis typically involves cell swelling, rupture of th…
Necrosis is a form of cell and tissue death that occurs when cells are damaged by injury, infection, loss of blood supply, or exposure to toxins, leading to their uncontrolled breakdown within living tissue. Unlike the orderly, programmed process of apoptosis, necrosis typically involves cell swelling, rupture of the cell membrane, and release of intracellular contents that can provoke surrounding inflammation. It can affect virtually any organ and is associated with causes such as ischemia, trauma, severe infection, and certain disease processes. The appearance and consequences of necrosis vary with its location and extent, and it is an important finding in the diagnosis and assessment of many conditions. Within the journal's broad coverage of thrombosis-related and biomedical research, related work includes a case report of Lennert lymphoma presenting with extensive necrosis, a case of irreversible cerebral necrosis following cardiorespiratory arrest, and studies examining tumour necrosis factor and oxidative-stress-related cell death in tissue. This page gathers peer-reviewed, open-access research relevant to necrosis, tissue injury, and the cellular processes that lead to cell death.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 70 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Necrosis, linking to each citing work.