Journal of Clinical Research In HIV AIDS And Prevention

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Clinical Research In HIV AIDS And Prevention-MRI-Manoj Sarma

United States

University of California,
Los Angeles.

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Manoj Sarma


10945 LeConte Avenue, 
Peter V. Ueberroth Building, Suite 1417A, 
Los Angeles, CA 90095-7206.

Research Interests:

MRI, MRS, Mathematics, Pulse Programming.


  • Dr. Manoj Sarma (Assistant Researcher, UCLA Radiological Sciences) was recently awarded a two-year R21 grant for his project entitled "Brain Connectivity, Cerebral metabolism and Neuropsychology in HIV Youths" by NINDS/NIH.
  • Although earlier neuroimaging studies investigated brain connectivity and neurochemical changes in HIV adults, brain connectivity changes have not been studied in perinatally HIV-infected youths. 
  • Also, the relationship of cerebral metabolic disturbance to neurocognitive and functional abnormalities in HIV has not been well delineated. 
  • Dr. Sarma's proposed work combining resting state functional Magnetic Resonance Imaging (MRI) with semi-LASER based 3D Magnetic Resonance Spectroscopic Imaging (MRSI) will impact the field with a better understanding of the functional neural and metabolic correlates in perinatally infected youths.
  • Dr. Sarma is working with Dr. Albert Thomas, Director of MR Spectroscopy at UCLA Radiology and a pioneer of various multi-dimensional MRSI techniques including 2D Localized correlated MR spectroscopy (L-COSY). 
  • This project will be in collaboration with Dr. Margaret Keller at Pediatric Infectious Diseases unit, Harbor-UCLA Medical Center. 
  • Dr. Sarma's specialty area of research includes development of novel in-vivo imaging techniques involving MRS/MRI for the study of brain, development and implementation of fast imaging techniques.
  • He has been working on MRI/MRSI pulse sequence development, signal processing, and data analysis within interdisciplinary teams in various projects like HIV-infected youths, obstructive sleep apnea, Hepatitis C, hepatic encephalopathy, prostate cancer, and Diabetes.