Toxicogenomics

Toxicogenomics is a field of science that studies the effects of environmental toxicants on the genome of an organism. It uses various technologies such as DNA microarray, next-generation sequencing, and computer modeling to monitor the changes in gene expression in response to a toxic stimulant. Toxicogenomics plays an important role in several areas, from drug discovery and development, to the understanding of the mechanisms of toxicity and disease onset, to the elucidation of genetic markers for human disorders. Research findings from toxicogenomics have been used for regulatory decision making, risk assessment, and public health protection. In summary, toxicogenomics is a powerful and growing field of research that can provide information on the biological effects of environmental contaminants to help protect public health.