Adverse Drug Reactions
Adverse drug reactions (ADRs) refer to unwanted or unintended effects of medications. They range from mild to life-threatening, and can occur in any phase of drug development, from preclinical trials to post-marketing surveillance. ADRs are a major public health concern due to the increasing number of drugs in the market, their complexity and potential consequences of untreated side effects. Adverse drug reactions can be prevented by careful monitoring during all phases of drug development, use of evidence-based clinical decision support, and providing clear information on drug indications and contraindications. ADRs can also be managed through drug utilization review, implementation of Pharmacovigilance programs, and patient education on the safe and effective use of medicines.
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