Aims and Scope
Aims and Scope
The journal takes its remit from both parts of its title. It considers substantive contributions to bioinformatics, to diabetes and related metabolic science, and to research that connects computational approaches with those conditions. Each domain is eligible on its own terms; a connection between them is welcome but not required.
- ISSN 2374-9431
- Publisher Open Access Pub
- Access Open access
- Review Peer-reviewed
Subject areas
The Journal of Bioinformatics and Diabetes publishes peer-reviewed research across two connected domains: computational and data-driven biology — genomic, transcriptomic, proteomic and metabolomic analysis, systems modeling, algorithms, databases and machine learning — and the biology, treatment and complications of diabetes and related metabolic disease. The boundary below is the journal’s, not the archive’s: it is stated so an author can decide before writing whether a manuscript belongs here.
Computational and data-driven biology
- Genomics and genetic variation
- Sequence analysis, variant annotation and functional prediction, association analysis, polygenic and population-genetic methods.
- Transcriptomics and epigenomics
- Expression analysis, regulatory-element and methylation studies, non-coding RNA, and single-cell approaches.
- Proteomics and metabolomics
- Protein and metabolite profiling, structural analysis, and the processing of mass-spectrometry and related data.
- Systems biology and modeling
- Pathway, network and constraint-based models of metabolism and signaling, and the evidence used to test them.
- Statistics and machine learning
- Algorithms, statistical methodology, predictive and classification models, and their validation on biological data.
- Resources and reproducibility
- Databases, ontologies, data standards, annotation, and analysis workflows described so that another group can run them.
Diabetes and metabolic science
- Mechanism
- Insulin production and action, glucose metabolism, oxidative stress, and the molecular processes through which diabetes develops.
- Forms and complications
- Type 1, type 2 and gestational diabetes, prediabetes, and complications across the eye, kidney, nerve, vascular and reproductive systems.
- Nutrition and pharmacology
- Nutrients, compounds and treatments examined experimentally or clinically, reported with the model, the doses and the conditions used.
- Measurement and diagnosis
- Measurement methods, monitoring technologies, diagnostic studies and clinical investigation in metabolic disease.
- Care and outcomes
- Self-management, health-services and informatics studies where the question concerns diabetes and metabolic health.
Evidence the journal considers
Subject eligibility is decided by the question a manuscript asks. How far its conclusions may reach is decided separately, by the evidence it presents.
- iFoundational and theoretical work, including method development and algorithmic contributions.
- iiComputational and analytical studies of existing or newly generated data.
- iiiLaboratory and experimental studies, including work in cell and animal models.
- ivClinical, epidemiological and health-services research in diabetes and metabolic disease.
- vTranslational work that connects a mechanism, a model or a dataset to practice.
- viWork that draws together and appraises findings already reported.
A manuscript is not required to contain a novel computational method, and it is not required to report a clinical intervention. It is required to ask a question that belongs to the remit above and to answer it with evidence appropriate to the claim it makes.
Eligibility and claims are judged separately
Two questions are asked of every submission, and they are not the same question.
Is the subject in scope?
This is settled by the remit above. A study of insulin signaling, a database of variant annotations, a trial of a dietary compound in a diabetic model and a review of measurement methods are all eligible subjects.
Does the evidence support the claim?
This is settled in review. Editorial decisions are based on scope, scientific quality, methodological rigor, ethical compliance, reporting quality, and relevance to the journal.
What review looks like
All submissions undergo initial editorial screening. Manuscripts that meet the journal's scope and minimum requirements proceed to independent peer review.
Single-blind by default; double-blind review is available on request.
What falls outside
Work with no substantive connection to bioinformatics, diabetes or metabolic science is returned at screening, as is work whose conclusions cannot be supported by the evidence presented.
Manuscript types
Seven types are open for unsolicited submission. The type describes the form of the contribution; the subject boundary is the one set out above.
- Research Article
- A full report of original work: the question, what was done, what was found and what follows from it.
- Review Article
- A critical synthesis of published work on a defined question, saying where the evidence is strong and where it is thin.
- Systematic Review and Meta-analysis
- A review carried out to a stated protocol, reporting the search, the selection of studies and, where applicable, the quantitative synthesis.
- Methods Article
- A new or substantially improved method, algorithm, analysis pipeline or laboratory protocol, described so that another group can apply it.
- Data/Resource Article
- A dataset, database, software tool or other resource, described together with how it was produced and how it can be reused.
- Short Communication
- A concise report of a finding that stands on its own.
- Case Report
- A clinical case or short series, presented for what it shows.
Editorial and Perspective/Commentary are commissioned by the editors. They are not part of the routine unsolicited submission categories.
A bioinformatics or data-oriented manuscript does not need a diabetes component to be eligible, and a diabetes or metabolic manuscript does not need a new computational method. Each is assessed on its own terms within the journal’s remit.
Where to read further
The pages that carry the requirements and the record behind this scope.
- Instructions for AuthorsPreparation, declarations and submission requirements.
- Editorial PoliciesEthics, authorship, peer review and corrections.
- ArchiveThe published record, by volume and issue.
- About the JournalWhy the journal exists and who it is written for.
Journal of Bioinformatics and Diabetes · ISSN 2374-9431 · Published by Open Access Pub.